Endocrine Disruptors

This conference delves right into the ongoing debate surrounding the complex identification of endocrine disruptors and the implementation of EU guidance documents. It offers participants valuable insights into the latest regulatory and scientific advancements.

The ECHA/EFSA guidance for the identification of Endocrine Disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009 requires a highly complex and challenging assessment for all active substances. With the new hazard classes for EDs under the CLP regulation, the challenge has recently been broadened. This conference will dive right into the debate surrounding Endocrine Disruptors and covers all the latest relevant regulatory and scientific developments.

The Conference will be taking place in Dusseldorf/Germany on 25 and 26 November 2025.

You can also follow all the exciting contributions via our live stream! Please find all information on the virtual participation here.

Highlights

Regulatory Developments and Future Perspectives

• ECHA on the implementation of the new CLP hazard classes for endocrine disruptors
• EDs under REACH and CLP: Experience from German UBA and BASF
• Outlook on REACH revision and GHS-related activities
• Pesticides: Updates and experience reports from the EU Commission, ANSES, and industry

Next Generation Testing and Innovative Methods

• BfR on current regulatory acceptance of NAMs
• Readiness of new ED testing methods
• Thyroid: Increasing confidence in the human thyroid microtissue assay
• Using AI: From QSAR predictions to LLM evidence summarisation

Developments in Ecotoxicology

• The SETAC MAPPED initiative
• Tiered assessment schemes linking NAMs to adverse outcomes in aquatic vertebrates

Beyond EATS: New Pathways and European Initiatives

• Next generation risk assessment of obesogenic chemicals: GOLIATH project findings and updates on PARC and AFARA initiatives
• Metabolism-disrupting chemical testing: Advances in methodology and future direction

Who should attend this conference?

Professionals working in the fields of:

• Toxicology and ecotoxicology
• Research and development
• Registration and regulatory affairs
• Chemical risk assessment
• Legal and general counselling

Sectors that should take part:

• Chemical/biocide/agrochemical/pharmaceutical/cosmetic industries
• Research institutes
• Regulatory authorities
• Environmental and health risk consultants
• Testing laboratories and contract research organisations (CROs)
• NGOs